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School of Pharmacy

To schedule an appointment or request general information, please contact: 

Department of Pharmaceutical Sciences 
410-532-5206

Education

• Ph.D., The University of Mississippi, Pharmaceutics Aug 2000 - May 2006, University, MS 38677, USA
• B. Pharm. Jadavpur University, Pharmacy Aug 1992 - Aug 1996, Calcutta, India

Research Interests

• Analytical Method Development & Pharmaceutical Analysis

  • Development and validation of reversed-phase HPLC stability-indicating methods
  • LC-MS/MS analysis for impurity detection and quantitation
  • Forced degradation studies of pharmaceutical compounds
  • Characterization of drug-excipient interactions

• Preformulation, Drug Stability Studies and Solubility/Stability Enhancement

  • Physicochemical characterization (preformulation) and stability of novel pharmaceutical compounds
  • pKa, log P, solubility, and pH stability profiling of drug molecules
  • Thermal analysis (DSC, TGA) for solid-state stability assessment
  • Drug-excipient compatibility studies
  • Inclusion complex formation of dietary supplements with cyclodextrins for enhanced solubility, stability and bioavailability

• Natural Products & Dietary Supplements

  • Stability and physicochemical characterization of natural products.  Current projects include curcumin, black cohosh, and St. John’s wort
  • Analytical method development for natural product bioactives

• Drug Development & Formulation

• Solid Dosage Forms
  • Development and optimization of immediate-release and controlled-release tablets and capsules
  • Formulation strategies for enhanced solubility and bioavailability of poorly soluble drugs
  • Roller compaction, high-shear granulation, direct compression, and multiparticulate coating
  • Tablet coating technologies (functional and non-functional)
  • Stability studies and quality control of solid formulations
• Semisolid Dosage Forms
  • Formulation of gels, creams, and ointments for topical and transdermal applications
  • Evaluation of rheological properties and drug release profiles
  • Development of bioadhesive and thermosensitive films for targeted delivery
  • Compatibility and stability studies of semisolid formulations
• Liquid Dosage Forms
  • Development of oral and parenteral solutions, suspensions, and emulsions
  • Preformulation strategies for solubilization and stabilization of poorly water-soluble drugs
  • Lyophilization and reconstitution studies for injectable formulations
  • Evaluation of pH, viscosity, and osmolality for formulation optimization

• Molecular Characterization & Computational Chemistry

  • Phase solubility and isothermal titration calorimetry for drug-cyclodextrin interactions
  • NMR spectroscopy for structural elucidation of drug complexes
  • Molecular modeling and molecular dynamics simulations of drug-excipient interactions

Certifications

• Pharmacist (RPh) Maryland License # 28501 March 28, 2022 – till date NPI: 1336881309
• Vaccination Maryland License # 28501 March 28, 2022 – till date Pharmacy Intern Maryland License# PI01474 Oct 23, 2017 – Dec 31, 2019
• FPGEC National Association of the Boards of Pharmacy Sept 29, 2017 BLS/CPR/First Aid American Heart Association April 2014 – Feb 2027

Biography

Dr. Asish K. Dutta is the Chair and Professor of Pharmaceutical Sciences at ��������, School of Pharmacy. He is also the Director of the Masters in Pharmaceutical Sciences program. He has over 23 years of academic experience teaching Pharmaceutics, Pharmacokinetics and Biopharmaceutics, Pharmaceutical Calculations and various didactic and research Electives. He is the Past-Chair of Pharmaceutics section of American Association of Colleges of Pharmacy (AACP) and currently actively participates at various committees and sub-committees at AACP. He is the Past-Chair of the Curriculum and Assessment Committees, member of Admissions and Student promotions committees for the School of Pharmacy, and Past-Chair of the Committee of Faculty Research and Development at ��������. He has over 20 years of experience at various stages of product and process development of pharmaceutical and nutraceutical products such as powders, immediate-release and controlled-release tablets and capsules, solutions, suspensions, ointments and creams, ophthalmic products, etc. Dr. Dutta has worked on several pharmaceutical products that are currently on the market. He also has an extensive experience in analytical method development and validation as well as preformulation analysis of active pharmaceutical ingredients and nutraceutical products. Dr. Dutta has extensively published his research in peer-reviewed journals, presented at national conferences and is a recipient of numerous intramural grants. He serves as a Reviewer for a number of journals and actively participates in Leadership roles at American Associations for Pharmaceutical Scientists (AAPS), such as the Chair of Abstract Screening Committee of FDD (Formulation and Drug Delivery) and the Chair of the Ambassador Program of MSE (Manufacturing Science and Engineering) sections. He has also served as the Student and Post-doc Outreach and Development (SPOD) Committee Representative of MSE, and is the past Co-Chair of Greater Maryland Discussion Group (GMDG-AAPS). Dr. Dutta holds a B.S. in Pharmaceutical Technology from Jadavpur University, and a Ph.D. in Pharmaceutics from University of Mississippi.

Publications

Book Chapter

1. Cantor, S. L., Dutta, A. K. “Analytical Testing and Evaluation of Capsules”, Pharmaceutical Dosage Forms-Capsules, Boca Raton, FL: CRC Press, Taylor and Francis, November 2017, pp. 345-372.

Manuscripts

1. Ryan Boasi, Pharm. D.; Attila J. Hertelendy, Ph. D.; Fadi Issa, MD; Christina Woodward, MD; Asish Kumar Dutta, Ph. D., RPh; Abeer Santarisi, MD, MSc; Dana Mathew, MD; Van Kenyan, MD; Miaka Huynh, Pharm. D., BCACP; Timothy J. Curtis, M. Sc., DPEM; Eric D. Miller, RN; Jacob Noel, MD; Eman Alshaikh, MD, MS; David DiGregorio, MSEM, MPAS; Amalia Voskanyan, RN; Gregory Ciottone, MD.  Illicit Fentanyls as Intentional Mass Casualty Threats: The added complexity of transdermal formulations. American Journal of Disaster Medicine, February 2025. Accepted.
2. Asish Dutta, Ph. D., Lauren Difalco, Fatima Karkoub, Ateeyah Atefat, Annesa Jugmohan.  “Validation of an Improved Reversed-Phase Stability-Indicating Method of Curcuminoids”, AACP Virtual Pharmacy Education 2020 Annual Meeting, July 13-31, 2020 poster abstract published in American Journal of Pharmaceutical Education 2020; 84 (6) Article 8220.
3. Park, E., Dutta, A. K., “Development and Validation of Improved Reversed-Phase HPLC Stability Indicating Method and Forced Degradation Studies of Curcuminoids”, AACP Annual Meeting, July 13-17, 2019, Chicago, IL, poster abstract published in American Journal of Pharmaceutical Education 2019; 83 (5) Article 7654.
4. Dutta, A. K. and Ikiki, E., “Novel Drug Delivery Systems to Improve Bioavailability of Curcumin”, Journal of Bioavailability and Bioequivalence, vol. 6, 2013, pp. 001-009.
5. Dutta, A. K., Stodghill, S. P. and Wyandt, C. M., “Physicochemical Characterization of NPC 1161C, A Novel Antimalarial 8-Aminoquinoline, in Solution and Solid State,” AAPS PharmSciTech, vol. 12, no. 1, 2011, pp. 177-191.
6. Dutta, A. K., Avery, B. A. and Wyandt, C. M., “Development and Validation of a Stability-Indicating Reversed Phase High Performance Liquid Chromatography Method for NPC 1161C, A Novel 8-aminoquinoline Antimalarial Drug,” Journal of Chromatography A, vol. 1110, 2006, pp. 35-45.
7. Dutta, A. K., Williamson, J. S. and Wyandt, C. M., “Solution-State Characterization of Inclusion Complexes of 8-Aminoquinoline with Sulfobutylether beta-Cyclodextrin Using Phase Solubility and Isothermal Titration Calorimetry,” AAPS Journal, vol. 7, no. S2, Nov 2005, Abstract T3150.
8. Dutta, A. K., Williamson, J. S. and Wyandt, C. M., “The Use of Isothermal Titration Calorimetry to Study the Complexation of 8-Aminoquinoline with Hydroxypropyl beta-Cyclodextrin and Sulfobutylether beta-Cyclodextrin,” AAPS Journal, vol. 7, no. S2, Nov 2005, Abstract T3151.
9. Dutta, A. K. and Wyandt, C. M., “Binary Phase Complexation of a weak base with Hydroxypropyl Beta-cyclodextrin in aqueous and buffer media,” AAPS Journal, vol. 6, no. 4, Nov 2004, Abstract M1190.
10. Dutta, A. K., Desai, P., Stodghill, S. P. and Wyandt, C. M., “Complexation of Hydroxypropyl Beta-cyclodextrin with a Novel Antimalarial drug, 8-Aminoquinoline,” AAPS PharmSci., vol. 5, no. 4, Oct 2003, Abstract M1194.
11. Dutta, A. K., Avery, B. A. and Wyandt, C. M., “Preformulation Studies of an 8- Aminoquinoline Derivative, a Novel Anti-malarial Drug – II,” AAPS PharmSci., vol. 4, no. 4, Nov 2002, Abstract T2335.

Poster Presentations

1. Asish Dutta, Ph. D., Lauren Difalco, Fatima Karkoub, Ateeyah Atefat, Annesa Jugmohan. “System Suitability, Interday-Intraday Accuracy and Precision, and Robustness of HPLC Stability Indicating Method of Curcuminoids”. Nancy Kreiter Research Day, ��������, School of Pharmacy, Department of Pharmaceutical Sciences, Baltimore, MD, USA, Apr. 20, 2020.
2. Park, E. and Dutta, A. K., “Development and Validation of Reversed-Phase HPLC Stability-Indicating Assay and Forced Degradation Studies of Curcumin,” Nancy Kreiter Research Day, ��������, School of Pharmacy, Department of Pharmaceutical Sciences, Baltimore, MD, USA, Apr. 26, 2019.
3. Park, E., Dutta, A. K., “Development of an Improved Reversed-Phase HPLC Stability Indicating Method and Forced Degradation Studies of Curcuminoids”, AAPS PharmSci 360 Annual Meeting, Nov 4-7, 2018, Washington, DC.
4. Acheampong, E., McHetz, E., Frempong, B., Feliciano, I. L., Desir, N. and Dutta, A. K., “Phytochemical Analysis of Black Cohosh, an Anti-Depressant Dietary Supplement for Women’s Health,” Nancy Kreiter Research Day, ��������, School of Pharmacy, Department of Pharmaceutical Sciences, Baltimore, MD, USA, Apr. 20, 2018.
5. Park, E. and Dutta, A. K., “Development of Reversed-Phase HPLC Stability Indicating Assay and Forced Degradation Studies of Curcumin,” Nancy Kreiter Research Day, ��������, School of Pharmacy, Department of Pharmaceutical Sciences, Baltimore, MD, USA, Apr. 20, 2018.
6. Yun, M., Raza, Z. and Dutta, A. K., “Development of a Stability-Indicating Reversed Phase HPLC Method of Curcumin, a dietary supplement,” Nancy Kreiter Research Day, ��������, School of Pharmacy, Department of Pharmaceutical Sciences, Baltimore, MD, USA, Apr. 21, 2017.
7. Dupont, L. and Dutta, A. K., “HPLC Method Development and Validation of Terbinafine and its Novel Formulations for tinea pedis,” Nancy Kreiter Research Day, ��������, School of Pharmacy, Department of Pharmaceutical Sciences, Baltimore, MD, USA, Apr. 24, 2015.
8. Dupont, L. and Dutta, A. K., “Formulation Development of Novel Bioadhesive in situ Transdermal Films in Patients with Diabetes mellitus,” Nancy Kreiter Research Day, ��������, School of Pharmacy, Department of Pharmaceutical Sciences, Baltimore, MD, USA, Apr. 24, 2015.
9. Tandoc, M. M. A., Cheung, R. and Dutta, A. K., “Development of a Stability-Indicating Reversed Phase HPLC method of St. John’s Wort, a Dietary Supplement for Women’s Health,” Nancy Kreiter Research Day, ��������, School of Pharmacy, Department of Pharmaceutical Sciences, Baltimore, MD, Apr. 25, 2014.  Received Graduate Scientific Poster Award.
10. Hochreiter, K. and Dutta, A. K., “Development of a Stability Indicating Reversed Phase HPLC method for Black Cohosh, a dietary Supplement for Women’s Health,” Nancy Kreiter Research Day, ��������, School of Pharmacy, Department of Pharmaceutical Sciences, Baltimore, MD, Apr. 25, 2014.
11. Salehani, F. and Dutta, A. K., “Gelatin Capsule Interactions & Stability with Dietary Supplements,” Nancy Kreiter Research Day, ��������, School of Pharmacy, Department of Pharmaceutical Sciences, Baltimore, MD, Apr. 25, 2014.
12. Dutta, A. K., Avery, B. A. and Wyandt, C. M., “Preformulation Studies of an 8-Aminoquinoline derivative, a Novel Anti-malarial drug,” AAPS-SRDG, University of Arkansas for Medical Sciences, School of Pharmacy, Little Rock, AR, May 29-30, 2003.

Professional Affiliations & Memberships

American Association of Colleges of Pharmacy (AACP), 2010-till date, Member
The Council of Independent Colleges (CIC), 2022- till date, Member
American Association of Pharmaceutical Scientists (AAPS), 2002 - till date; Member
Greater Maryland Discussion Group (GMDG-AAPS), 2011-2016; Steering Committee Member, Co-Chair
Southern Regional Discussion Group (SRDG)-AAPS, 2002 to 2006; Member
The University of Mississippi Student Chapter-AAPS, 2003 to 2006; Member
Phi Kappa Phi Honors Society, Initiated in 2002; Member
Rho Chi Honors Society, Initiated in 2002; Member

Awards

Pangborn Travel Award, $750.00                                         July 2023

��������, Attending American Association of the Colleges of Pharmacy (AACP) Annual Meeting 2023, Denver, CO.

Pangborn Travel Award, $2008.00                                      June 2022

��������, Attending Council of Independent Colleges (CIC) Chairs’ Workshop, Phoenix, AZ, June 2022.

Plaque of Appreciation as Chair, Pharmaceutics Section  July 2021

American Association of Colleges of Pharmacy (AACP)

Pangborn Travel Award, $1200.00                                       July 2019

��������, Attending American Association of the Colleges of Pharmacy (AACP) Annual Meeting 2019, Chicago, IL.

Pangborn Travel Award, $1200.00                                       Nov 2018

��������, Poster Presentation at American Association of Pharmaceutical Scientists Annual Meeting PharmSci 360, Washington, DC.

Pangborn Travel Award, $700.00                                         July 2018

��������, Attending American Association of the Colleges of Pharmacy (AACP) Annual Meeting 2018, Boston, MA.

Certificate of Appreciation as Steering Committee Member       Jan 2018

Greater Maryland Discussion Group (GMDG)-AAPS

Certificate of Appreciation as Chair, MSE Ambassador Program                                                                                                   Jan 2018

Nov 2016- Nov 2017, American Association of Pharmaceutical Scientists (AAPS)

Certificate of Appreciation as Chair, MSE Ambassador Program                                                                                                  Dec 2016

2015- Nov 2016, American Association of Pharmaceutical Scientists (AAPS)

Certificate of Appreciation as Co-Chair                               Jan 2015

Greater Maryland Discussion Group (GMDG)-AAPS

Certificate of Appreciation for “Partners in Mission” Summer 2014

Recognition of 5 years of dedication and service, ��������, Baltimore MD

Certificate of Appreciation, Leadership Academy for Teens (LIFT)                                                                                July 19, 2013

Holding Session in Careers in Pharmacy, ��������, Baltimore, MD.

AstraZeneca Travel Award                                                           2005

American Association of Pharmaceutical Scientists (AAPS), 2005 Annual Meeting and Exposition, Nashville, TN.

Graduate School Travel Award                                           Nov, 2004

The University of Mississippi, Poster Presentation at AAPS 2004 Annual Meeting and Exposition, Baltimore, MD.

Graduate School Travel Award                                            Oct, 2003

The University of Mississippi, Poster Presentation at AAPS 2003 Annual Meeting and Exposition, Salt Lake City, UT.

Summer Research Fellowship                                       Summer, 2003

The University of Mississippi, Graduate School for Academic Excellence.

Graduate School Travel Award                                           Nov, 2002

The University of Mississippi, Poster Presentation at AAPS 2002 Annual Meeting and Exposition, Toronto, Canada.=

Rho Chi Honor Society                                                                  2002

The University of Mississippi, Academic and Scholastic achievements.

Phi Kappa Phi Honor Society                                                       2002

The University of Mississippi, Superior Scholastic, Academic achievements (GPA 4.0) and Good Character.